Methyl-Beta-Cyclodextrin

Methyl-Beta-Cyclodextrin

Details
This product is a white ultrafine powder with good fluidity. It does not float or aggregate in water and dissolves quickly upon sinking. It has no peculiar smell and a slightly sweet taste. Methylated β-cyclodextrin is an excellent solubilizer, stabilizer and sustained-release agent. It has a relatively high surface tension and is particularly effective in increasing the water solubility of oil-soluble molecules.
Category
Pharmaceutical Cyclodextrin
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Description
Technical Parameters

Methyl-Beta-Cyclodextrin

 

 

This product is a white ultrafine powder with good fluidity. It does not float or aggregate in water and dissolves quickly upon sinking. It has no peculiar smell and a slightly sweet taste. Methylated β-cyclodextrin is an excellent solubilizer, stabilizer and sustained-release agent. It has a relatively high surface tension and is particularly effective in increasing the water solubility of oil-soluble molecules.

 

Basic Information Introduction

 

Chinese Name

Methyl-Beta-Cyclodextrin

Other Names

Methyl-β-Cyclodextrin, Methyl-beta-Cyclodextrin

English Name

Methyl-Beta-Cyclodextrin; Methyl-β-Cyclodextrin

Abbreviation

MEBCD

CAS No.

128446-36-6

Molecular Formula

C42H70-nO35·(CH3)n

Molecular Weight

1135 + n·(14.0)

 

Test Standard

 

Test items

Enterprise standard

Properties

This product is white powder; odorless, slightly sweet; easily soluble in water and methanol, easily soluble in ethanol and ethylene glycol, almost insoluble in cyclohexane and ethyl acetate

Content

≥98%

Specific rotation

+154°~+165°

pH

pH5.0~7.5

Clarity of solution

2.5g/25ml aqueous solution is clear

Absorbance of impurities

The absorbance within the wavelength range of 220~350nm shall not exceed 1.0

The absorbance within the wavelength range of 350~750nm shall not exceed 0.1

Average degree of substitution

7.0~13.3

Loss on drying

≤7.0%

Beta-cyclodextrin

≤0.2%

Ignition residue

≤0.5%

Heavy metals

≤10ppm

Chloride

≤0.2%

Total number of aerobic bacteria

≤1000cfu/g

Total number of molds and yeasts

≤100cfu/g

Escherichia coli

Not to be detected

 

Product Features

 

Among the common cyclodextrin derivatives, methyl-β-cyclodextrin has relatively high surface tension. This product is a white fine granular substance with good fluidity. It sinks and dissolves when entering water; it has no peculiar smell and tastes slightly sweet; it is highly soluble in water and methanol, and easily soluble in ethanol and ethylene glycol, but almost insoluble in cyclohexane and ethyl acetate.

 

Product Application

 

Due to the excellent solubilizing and encapsulating effects of methyl-β-cyclodextrin, and because it is soluble in both water and organic solvents, it is widely applied in medicine, food, pesticides, cosmetics, daily chemicals, chemical industry, textile dyeing and finishing, chromatographic analysis, and functional materials. Specifically, it can be manifested as follows:

1. It can increase solubility and utilization rate, enhancing the effect or reducing the dosage;

2. It can adjust or control the release rate of the encapsulated substances;

3. It can enhance the stability of the encapsulated substances, especially more effective in increasing water solubility for oil-soluble molecules.

 

Packaging and Storage

 

  • Packaging Specifications: 100g/500g/1kg/2kg/10kg
  • Packaging Form: Medical low-density polyethylene bag + carton or cardboard barrel
  • Storage Method: Store in a dark place and sealed

 

 

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