2,6-Dimethyl-β-cyclodextrin

2,6-Dimethyl-β-cyclodextrin can enhance the solubility and bioavailability of drugs, increase the therapeutic effect of pharmaceuticals or reduce the dosage.

Basic Information

Chinese Name	2,6-Dimethyl-β-Cyclodextrin
Alternative Name	DMBCD
English Name	2,6-di-O-methyl-beta-Cyclodextrin; 2,6-di-O-methyl-β-Cyclodextrin
CAS No.	51166-71-3
Molecular Formula	C₅₆H₉₈O₃₅
Molecular Weight	1331.36

Product Performance

Among common cyclodextrin derivatives, 2,6-dimethylated cyclodextrin has a relatively high surface tension. 2,6-Dimethyl-β-cyclodextrin is a cyclodextrin derivative with high water solubility and stability, and is widely used in various fields such as medicine, daily chemicals, and food. It is mainly used to increase drug solubility, enhance stability, control release rate, and improve product performance.

In the medical field

It increases drug solubility and bioavailability, enhancing the efficacy of the drug or reducing the dosage. It adjusts or controls the release rate of the drug. It reduces the toxic and side effects of the drug. It enhances the stability of the drug, especially significantly improving the water solubility of oil-soluble molecules.

In daily chemicals and cosmetics

It reduces microbial contamination and keeps the skin moist. It masks unpleasant odors and promotes the transdermal absorption of active ingredients. It reduces skin irritation.

In the food industry

It serves as a stabilizer for flavors and pigments, improving their stability and longevity. It masks unpleasant odors and improves product taste.

In other fields

It is used in pesticides, the chemical industry, dyeing and finishing of textiles, chromatographic analysis, and functional materials.

Testing Standards

Test items	Enterprise standard
Properties	This product is white powder; odorless, slightly sweet; easily soluble in water and methanol, easily soluble in ethanol and ethylene glycol, almost insoluble in cyclohexane and ethyl acetate
Content	≥98%
Specific rotation	+154°～+165°
pH	pH5.0～7.5
Clarity of solution	2.5g/25ml aqueous solution is clear
Absorbance of impurities	The absorbance within the wavelength range of 220～350nm shall not exceed 1.0 The absorbance within the wavelength range of 350～750nm shall not exceed 0.1
Average degree of substitution	7.0~13.3
Loss on drying	≤7.0%
Beta-cyclodextrin	≤0.2%
Ignition residue	≤0.5%
Heavy metals	≤10ppm
Chloride	≤0.2%
Total number of aerobic bacteria	≤1000cfu/g
Total number of molds and yeasts	≤100cfu/g
Escherichia coli	Not to be detected